Jentadueto 2.5mg/500mg pill ( international brand version ), Trajenta Duo has two active ingredients, metformin and linagliptin. This medication is prescribed to people with increased blood sugar levels or type 2 diabetes. Additionally, this medication is classified under the drug class known as antidiabetics. Both active ingredients have different mechanisms of action:

• Metformin works by limiting glucose production in the liver, improving insulin resistance, and slowing down glucose absorption in the intestine.

• In contrast, another active ingredient, linagliptin, stimulates the pancreas to maximize insulin production and decreases the hormone that causes a spike in blood sugar levels.

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All the health and medical information given over here is for general purposes only. Always consult your healthcare provider before purchasing any of the medications to confirm whether this medicine is appropriate, safe, and effective for your condition, and is safe, appropriate, or effective for you. Always consult your health care professional before using this, or any other, drug.

Make sure to go through the following preventive measures before starting the treatment:

• Have a look through the list of ingredients before starting the treatment to avoid any allergies you may have to the active/inactive ingredients. If taken despite being allergic to it, it may cause a wide range of complications.

• Your kidneys must function normally to take this medication. If you are not aware of your kidney’s health, you may be requested to undergo a few tests. If you have any kidney problems, let your doctor know before starting the treatment.

• If used by people with acute or chronic metabolic acidosis, it may bring about a wide range of complications. Before beginning the treatment, please inform your doctor if you have a history of metabolic acidosis or diabetic ketoacidosis.

Common side effects

• Nausea
• Vomiting
• Dizziness
• Headache
• Fatigue
• Skin rash
• Abnormal liver function

Serious side effects:

Severe allergic reaction: Breathing problems or wheezing, racing heart, fever or general ill feeling, swollen lymph nodes, red bumps on the skin called hives, nausea or vomiting, swelling of the face, lips, mouth, tongue, or throat, trouble swallowing or throat tightness, itching, skin rash.

Lactic acidosis: General ill feeling, difficulty breathing, stomach pain, muscle pain, drowsiness

Vitamin B12 deficiency: Cold hands and feet, fast or abnormal heartbeat, pale or yellowish skin, dizziness, lightheadedness, unusual weakness or tiredness, feeling like you are about to faint, shortness of breath

Severe skin reactions: Bullous pemphigoid, which starts as a skin rash and large blisters on the skin

Heart failure: Unusually fast weight gain, shortness of breath or trouble breathing, unusual tiredness, swelling in your feet, ankles, or legs

Please follow the directions mentioned below throughout the treatment for maximum results:

• Make sure the Trajenta Duo 2.5 mg/850mg tablet is not within the reach of children, addicts, and pets.

• Refrain from sharing it with other people, no matter how identical their situation or symptoms appear.

• It should be used with extreme caution in people aged above 65 due to the increased side effects.

• Please contact your medical provider to know the correct dosage.

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